Jovita Mezquita obtained the MD degree at the Faculty of Medicine of the University of Barcelona (1972) and her Ph.D. on the Characterization of Phosphoglyceratemutases (1978), in the same University, with Professor Josep Carreras. Afterwards, with Professor Cristóbal Mezquita, she became involved in the study of Nuclear Proteins, finding that a heat stable factor, that turned out to be ubiquitin, was an activator of the histone deacetylase activity in vitro.

Jovita Mezquita has an extensive knowledge in molecular genetics, after her training experience in the Laboratory of Medical Biochemistry at the University of Calgary (Alberta, Canada) and in the University of North Carolina at Chapel Hill (USA).

From 1981 to 1985 she had the opportunity to learn pioneer techniques in recombinant DNA and the Maxam and Gilbert sequencing method, in the laboratory of Professor Gordon H. Dixon, where she enrolled in the project of characterization, sequencing and expression of the histone genes of the trout, devoting primarily her work to histone H1 gene. She likes to mention the exciting working climate of the laboratory of Gordon H. Dixon, who so enthusiastically introduced her to the histone genes project, and Wayne Connor, from whom she learned many of the secrets of molecular genetics.
 


On 1984 she moved to the University of North Carolina at Chapel Hill (USA) to learn the alternative dideoxi sequencing method developed by Sanger, with Professor Alan T. Bankier. Subsequently, she introduced this sequencing technique, that would become today's standard, in the University of Calgary. Given the simplicity and strengh of the method, she managed the task of developing a strategy to isolate and characterize the chicken protamine gene, for which there was no homologous probe available.

On 1986 she moved back to her actual position in the Molecular Genetics Laboratory.



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